Medicinal Chemistry

Medicinal chemistry involves the discovery, development, identification & interpretation of the mode of action of biological active compound at the molecular level. Emphasis is put on drugs, but the significance of medicinal chemistry is also concerned with the study, identification, interpretation & synthesis of the metabolic products of drug and related compounds.

Bacterial Cell Wall

Medicinal Chemistry

The success of antibacterial agents owes much to the fact that they can act selectively against bacterial cells rather than animal cells. This is largely because bacterial and animal cells differ both in their structure and in their biosynthetic pathways. Let us consider some of the differences between the bacterial cell (defined as prokaryotic ) […]

History of Anti-Bacterial agents

Medicinal Chemistry

There is evidence of antibacterial herbs or potions being used for many centuries. For example, the Chinese used moldy soybean curd to treat carbuncles, boils, and other infections. Greek physicians used wine, myrrh, and inorganic salts. In the Middle Ages, certain types of honey were used to prevent infections following arrow wounds. Of course in […]

Drug Targets at the Molecular Level

Medicinal Chemistry

The main molecular targets for drugs are proteins (mainly enzymes, receptors, and transport proteins) and nucleic acids (DNA and RNA). These The main molecular targets for drugs are proteins (mainly enzymes, receptors, and transport proteins) and nucleic acids (DNA and RNA). These are large molecules ( macromolecules ) that have molecular weights measured in the […]

Drug Targets: Understanding Cell Structure

Medicinal Chemistry

Why should chemicals, some of which have remarkably simple structures, have such an important effect on such a complicated and large structure as a human being? The answer lies in the way that the human body operates. If we could see inside our bodies to the molecular level, we would see a magnificent array of […]

What is a drug?

Medicinal Chemistry

The medicinal chemist attempts to design and synthesize a pharmaceutical agent that has a desired biological effect on the human body or some other living system. Such a compound could also be called a ‘drug’, but this is a word that many scientists dislike because society views the term with suspicion. With media headlines such […]

Introduction to General Anesthetics

Medicinal Chemistry

General anaesthesia are CNS depressant that produce anaesthesia, which extends to the entire body and are characterised by a state of unconsciousness, analgesia and Amnesia with skeleton muscle relaxation and loss of reflexes. General anaesthetic are employed for surgical operations and four stages of anaesthesia may be recognised as: Stage 1 (Analgesia): The patient is […]

Pharma Hub

Medicinal Chemistry

Bacterial Cell Wall

History of Anti-Bacterial agents

Drug Targets at the Molecular Level

Drug Targets: Understanding Cell Structure

What is a drug?

Introduction to General Anesthetics